Rod Brewer attended the University of Florida in Gainesville, Florida, where he played for coach Joe Arnold's Florida Gators baseball team from 1985 to 1987. In 1986, he played collegiate summer baseball with the Hyannis Mets of the Cape Cod Baseball League. The St. Louis Cardinals selected Brewer in the fifth round of the 1987 MLB Draft. He would go on to play 4-years for the St. Louis Cardinals, finishing with a lifetime.278 average in the Major Leagues. Following his stint as a Cardinal, Rod also played in the Japan, Nippon Professional Baseball League before retiring from baseball.